Eyelash serums do not contain real hormones. Most use natural ingredients like peptides, vitamins, and plant oils. However, some products contain prostaglandin analogs – these are artificial substances that act similarly to hormones. They can make your eyelashes grow faster but can also cause side effects. In this article, you will find out what ingredients are really in eyelash serums and which product suits you best.


Key Takeaways

  • Eyelash serums do not contain real hormones, but some have hormone-like substances such as prostaglandin analogs

  • These substances can accelerate eyelash growth, but scientific studies show possible side effects such as eye irritation and skin discoloration

  • Natural eyelash serums with peptides, biotin, and vitamins are gentler and safer, especially if you have sensitive eyes

  • The choice depends on your goals: Fast, dramatic results or long-term, gentle care


What are eyelash serums and what ingredients do they contain?

Eyelash serums are like vitamins for your eyelashes. They do not contain hormones in the classic sense. Instead, most eyelash serums contain peptides, vitamins, and natural oils that make your eyelashes stronger and healthier.

Detailed overview of ingredients in Sins 'n Lashes Eyelash Serum

Think of peptides as small building blocks that help your body produce keratin. Keratin is the protein your eyelashes are made of. The more keratin, the stronger your eyelashes. These bio-peptides act similarly to hormones, but are much gentler and usually cause no problems.

Another popular ingredient is biotin (also called Vitamin B7). According to the Cleveland Clinic, biotin helps your body form more keratin. It improves your metabolism and thus indirectly supports healthy hair growth.

Then there are prostaglandin analogs – that is the complicated term for artificial substances modeled after the body's own prostaglandin. They act similarly to hormones and can make your eyelashes grow significantly faster. But be careful: They can also have side effects that you should know about.

Overview of the most important ingredients

Bio-Peptides (Amino Acid Chains)

These small protein building blocks tell your hair follicles: "Produce more keratin!" The result: Your eyelashes become stronger, thicker, and break less easily. Unlike harsh chemicals, bio-peptides are super gentle and perfect for sensitive eyes.

Biotin (Vitamin B7)

Biotin is like a turbo for your metabolism. It helps your body process proteins better – and since eyelashes mainly consist of protein, they benefit directly from it. Healthline explains that biotin can work wonders, especially for people with biotin deficiency.

Prostaglandin Analogs (Artificial Growth Agents)

These substances prolong the growth phase of your eyelashes. Imagine your eyelashes are normally in the growth phase for 30 days – prostaglandins prolong this phase so they become longer and thicker. Sounds great, but there is a catch: possible side effects.


Are eyelash serums with prostaglandin analogs dangerous?

Eyelash serums with prostaglandin analogs (like bimatoprost or isopropyl cloprostenate) really work. Research results show that they can significantly improve eyelash length and density. But as with many things in life: where there is light, there is also shadow.

The effect is impressive: These substances prolong the growth phase of your eyelashes and improve blood circulation to the hair follicles. This means more nutrients and oxygen for your eyelashes. But here come the possible problems:

What can happen? The most common side effects

Red, irritated eyes

This is the most common side effect. Clinical studies show that about 17% of users get red eyes. It feels like after a long day at the computer – uncomfortable, but usually not dangerous.

Dark discoloration of the skin

The skin around your eyes can darken. This looks like slight dark circles and usually disappears when you stop using the serum. Scientific studies show that about 5% of users can develop skin discoloration.

Fat loss around the eyes (Periorbital Fat Loss)

This is the most worrying effect. In some people, the fat around the eyes breaks down, which can lead to sunken eyes. Research shows that users of prostaglandin serums have significantly more volume loss around the eyes than non-users.

Eyelash loss after discontinuation

As soon as you stop using the serum, your eyelashes often fall out more. Why? Your hair follicles get used to the artificial stimulation. When this stops, they need time to get used to the natural rhythm.


How do prostaglandin analogs work in eyelash growth?

Let's simplify this: Your eyelashes go through three phases – like a seasonal cycle.

Eyelash growth cycle Transition phase Resting phase
Anagen (30-45 days) Catagen (2-3 weeks) Telogen (100 days)

The Eyelash Life Cycle (Simply Explained)

Phase 1: Growth (Anagen Phase) – 30 to 45 Days

Your eyelash is actively growing. This is like spring and summer for your hair. During this time, it should become as long and strong as possible.

Phase 2: Transition (Catagen Phase) – 2 to 3 Weeks

Growth stops. The hair follicle shrinks. This is like autumn – the eyelash is preparing to fall out.

Phase 3: Rest (Telogen Phase) – 100 Days

The eyelash rests, finally falls out, and a new one begins to grow. This is winter.

How prostaglandin analogs work: They artificially prolong Phase 1. Instead of 30 days, your eyelash might grow for 50 days. Animal experiments confirm that substances like bimatoprost significantly increase eyelash length.

If you prefer natural methods, read our guide Longer eyelashes at home: These methods really work. There we show you step by step which care routines really help.


Comparison: Eyelash Serums with and without Prostaglandin Analogs

Imagine you are standing in front of two doors. Both lead to longer eyelashes, but the path is different.

Eyelash Serum Comparison: Hormones vs. Natural Ingredients

Door 1: Eyelash Serums with Prostaglandin Analogs

The fast way. You see the first visible results in just 4 to 8 weeks, maximum results after 12 to 16 weeks. Your eyelashes can become up to 25% longer and 106% fuller. Sounds fantastic, right? But the price: possible eye irritation, skin discoloration, and the risk of fat loss around the eyes.

Door 2: Natural Eyelash Serums (without Prostaglandin Analogs)

The gentle way. These serums use peptides, biotin, pumpkin seed oil, and plant-based keratin. They care for your eyelashes like a good hair treatment. The results are subtler and take longer (8 to 12 weeks for the first visible improvements), but the risk of side effects is minimal. Dermatology experts confirm: These serums are ideal for sensitive eyes.

By the way: Many eyelash serums also work for eyebrows. You can learn more about this in our article on Differences between Eyelash and Eyebrow Serums.

Quick Comparison: Which Serum Suits You?

What matters to you With Prostaglandin Analogs Natural Alternative
Main Ingredients Bimatoprost, Isopropyl Cloprostenate Biotin, Peptides, Pumpkin Seed Oil, Keratin
How it works Artificially prolongs the growth phase Strengthens and nourishes hair follicles naturally
Results Fast & dramatic (visible in 4-8 weeks, max. 12-16 weeks) Slower & gentler (visible in 8-12 weeks)
Side Effects Eye irritation, discoloration, fat loss Minimal to none
After Discontinuation Eyelashes often fall out more heavily Eyelashes remain healthy
Best for Quick results, insensitive skin Sensitive eyes, long-term care
Approval FDA-approved (Bimatoprost) Cosmetic products, not regulated

Which eyelash serum is better: Natural or with Prostaglandin Analogs?

That's like asking: "What is better – running or cycling?" The answer: It depends on what you want to achieve.

Choose natural eyelash serums if you...

  • Have sensitive eyes or wear contact lenses

  • Are looking for a long-term care routine that you can use for years

  • Value vegan, cruelty-free products

  • Want to use the serum for your eyebrows too

  • Want to avoid side effects

Expert reviews confirm: Non-prostaglandin serums are safer for daily use, especially on sensitive skin.

Choose prostaglandin analogs if you...

  • Want quick, visible results in a few months

  • Have robust skin and rarely react allergically

  • Are willing to use the product under medical supervision

  • Can deal with possible side effects

  • Only want to use the serum for a short time

For a comprehensive eyelash care routine, we recommend: No matter which serum you choose, pay attention to gentle cleansing, avoid aggressive eyelash curlers, and give your eyelashes make-up-free days regularly.


Common myths about eyelash serums – What is really true?

There are many half-truths about eyelash serums. In our article on the biggest myths about eyelashes and eyelash serums, we clear up the most common misconceptions. Here are the most important ones:

Myth 1: "All eyelash serums contain hormones"

Truth: No. Most contain peptides and vitamins. Only some have hormone-like prostaglandin analogs – but these are not real hormones.

Myth 2: "More expensive serums are automatically better"

Truth: Price says nothing about quality. An inexpensive serum with biotin and peptides can be just as effective as an expensive product. Look at the ingredients, not the price.

Myth 3: "I see results after a week"

Truth: Patience is key. Natural serums take 8-12 weeks, prostaglandin serums 4-8 weeks for first visible improvements. Eyelashes grow slowly – that is normal.

Myth 4: "Once applied, longer forever"

Truth: As soon as you stop, your eyelashes return to their natural state. Eyelash serums are like exercise – the results only stay if you stick with it.


Eyelash care in different phases of life: What changes?

Your eyelashes age with you. What works at 25 may not be enough at 45. In our guide Eyelash care for every phase of life, you will find out how to adjust your routine.

In your 20s and 30s: Prevention is everything

  • Use natural eyelash serums with peptides and biotin

  • Remove make-up thoroughly – every evening, without exception

  • Avoid excessive crimping with the eyelash curler

  • Give your eyelashes regular extension-free phases

In your 40s and 50s: Intensive care becomes more important

  • Rely on moisturizing products

  • Use nutrient-rich serums with vitamins

  • Ensure a balanced diet with Omega-3 fatty acids

  • Use gentle, sulfate-free cleansers

From 60 years on: Focus on protection and strengthening

  • Choose hypoallergenic, gentle products

  • Hydration is doubly important now

  • Avoid aggressive treatments like perms

  • Rely on natural serums instead of harsh chemicals


Eyelash Serums: The Fact Check

Here are the most important answers to the most common myths about eyelash serums summarized at a glance:

1. What is mainly contained in eyelash serums?

✅ Peptides, vitamins, and sometimes hormone-like substances

2. What are prostaglandin analogs?

✅ Artificial substances that accelerate eyelash growth

3. What ingredients are in natural eyelash serums?

✅ Biotin, peptides, pumpkin seed oil, plant-based keratin

4. What are possible side effects of prostaglandin analogs?

✅ Eye irritation, skin discoloration, fat loss around the eyes

5. What is the main advantage of natural eyelash serums?

✅ They are gentle, safe, and have hardly any side effects

 


Conclusion: What you need to know about eyelash serums and hormones

The short answer: Eyelash serums do not contain real hormones. Most use natural peptides, vitamins, and plant oils. Some products use prostaglandin analogs – artificial substances that act similarly to hormones.

The details: Scientific studies show that prostaglandin analogs deliver impressive results – up to 25% longer and 106% fuller eyelashes in 16 weeks. But they also have downsides: eye irritation in 17% of users, skin discoloration in about 5%, and possible fat loss around the eyes.

Natural eyelash serums are gentler. They take longer (8-12 weeks for first visible improvements) but cause hardly any side effects. Perfect for sensitive eyes, contact lens wearers, and anyone looking for a long-term care routine.

Your decision depends on:

  • How fast do you want to see results?
  • How sensitive are your eyes?
  • Do you want to use the serum long-term?
  • Are you willing to risk possible side effects?

Whatever choice you make: Inform yourself well, read the ingredients, and listen to your body. If in doubt, ask your doctor or dermatologist.


Start your safe eyelash routine now – without hormones, with maximum care

If you are looking for a gentle, highly effective eyelash serum without prostaglandin analogs, our natural eyelash serum is just right for you. Developed in Germany, dermatologically tested, and loved by over 207,000 followers.

Why Sins'n Lashes Lash Serum is the best choice:

Ideal for sensitive eyes – Ophthalmologically tested, no irritation

Without hormones & without prostaglandin derivatives – Zero risk for dangerous side effects

Power ingredients from nature – Biotin, peptides, pumpkin seed oil, ginseng, panthenol, vegan keratin

Visible results – Longer and fuller eyelashes within 8-12 weeks with daily use

100% vegan & cruelty-free – No parabens, oils, or silicones

Made in Germany – Highest quality standards and safe formulation

Perfect combination for eyelashes & eyebrows

Save now with our Perfect Duo Bundle – Eyelash Serum + Eyebrow Serum at a bargain price.

Bonus Tip: Combine your eyelash serum with our 100% Pure Rosemary Oil for holistic hair and eyelash care.

Your advantage today:

🚚 Free shipping – Within Germany

Fast delivery – Shipping within 24 hours

💰 Satisfaction guarantee – 30 days money back

👉 Order now and get longer eyelashes without hormones


Frequently Asked Questions (FAQ)

How often should I apply eyelash serum?

The answer: Once daily, ideally in the evening after facial cleansing. Apply the serum directly to the lash line – like an eyeliner. Consistency is key to success. Natural serums take 8-12 weeks, prostaglandin serums 4-8 weeks for first visible results.

Find more tips in our guide to the perfect eyelash care routine.

Are there side effects with natural eyelash serums?

The answer: With natural serums containing peptides and plant extracts, side effects are extremely rare. Some people report slight tingling upon first application – this is normal and disappears after a few days.

In contrast, clinical studies show that prostaglandin serums cause eye redness in 17% of users. Natural alternatives are much better tolerated.

Can I use eyelash serum with sensitive eyes?

The answer: Yes, but choose a prostaglandin-free, natural serum. Do a patch test beforehand: Apply the serum to a small spot on your forearm and wait 24 hours. No reaction? Then you can use it safely.

If you have an eye condition (e.g. glaucoma), talk to your doctor first. Our natural eyelash serum is specially developed for sensitive eyes and dermatologically tested.

Where can I buy high-quality eyelash serums without hormones?

The answer: Directly from us! Our natural eyelash serum is free from prostaglandin analogs and contains only high-quality, plant-based ingredients. With over 207,000 Instagram followers and thousands of satisfied customers, we are proud of our "Made in Germany" quality.

Free shipping today + 30-day money-back guarantee.

Do home remedies work as well as eyelash serums?

The answer: Partially. Home remedies like castor oil, Vitamin E oil, or our Rosemary Oil can support eyelash growth. Cleveland Clinic confirms that a balanced diet with biotin and Omega-3 also helps.

But: Specially formulated eyelash serums have a higher concentration of active ingredients and are optimized for maximum absorption. Home remedies are a good addition, but not a complete replacement.

Can I use eyelash serum during pregnancy or breastfeeding?

The answer: With natural serums without prostaglandin analogs, there are normally no concerns – they only contain plant extracts, peptides, and vitamins. Absolutely avoid prostaglandin analogs during pregnancy and breastfeeding.

Still, talk to your doctor beforehand, because every pregnancy is different. Safety always comes first.

How long does it take to see results?

The answer: That depends on the product type:

  • Natural eyelash serums: First improvements after 8-12 weeks, maximum results after 16-20 weeks
  • Prostaglandin analogs: First changes after 4-8 weeks, maximum results after 12-16 weeks
Why so long? Because the natural eyelash cycle lasts 4-6 months. Your eyelashes must first go through all three phases (growth, transition, rest) before you see the full effect. Patience is rewarded!

Find more info in our article about Eyelash Serum

 


Sins 'n Lashes Beauty Editorial Team

Experts in natural eyelash care | Made in Germany 🇩🇪

Our team of beauty experts, dermatologists, and cosmetic chemists has been developing high-quality, natural eyelash care products for years. We rely on scientifically proven ingredients without aggressive chemicals – for healthy, long eyelashes without compromise.

Our Mission: To help everyone achieve beautiful, healthy eyelashes – with transparent information and honest products that really work.

Expertise:
Eyelash Care Natural Cosmetics Dermatology Product Development

📧 Questions? Contact us: info@sinsnlashes.com
📱 Follow us on Instagram: @sinsnlashes

Note: This article serves for information purposes only and does not replace medical advice. In case of eye problems or uncertainties, please consult a doctor or dermatologist.